浙江3市儿童血清中脂溶性维生素水平比较  

Investigation of Serum Level of Fat-soluble Vitamins Among Urban Children in Zhejiang Province

作　　者：张慧芬[1] 邵裕坤[1] 赵正言[1] 王珏[1] 朱红[1] 郦柏平[1] 徐勤伟[2] 周冬儿[2] 

机构地区：[1]浙江大学医学院附属儿童医院,杭州市310003 [2]浙江大学医学院,杭州市310027

出　　处：《中国药房》2007年第2期116-118,共3页China Pharmacy

摘　　要：目的:比较浙江3市儿童血清中脂溶性维生素水平。方法:以高效液相色谱法测定血清中脂溶性维生素浓度。结果:274份血样维生素E、维生素A和β-胡萝卜素含量分别为(9．02±2．36)、(0．53±0．10)、(0．23±0．16)μg·mL-1;25-羟基维生素D3和维生素D3检出率分别为75．55％、51．10％,检出浓度分别为(18．51±7．64)、(20．83±10．67)ng·mL-1。5种脂溶性维生素水平没有性别差异(P>0．05),但地区间差异明显(P<0．01或P<0．05)。结论:浙江3市儿童血清中维生素E、维生素A和β-胡萝卜素营养状况比较理想,但25-羟基维生素D3与维生素D3偏低较为普遍。OBJECTIVE： To investigate and compare the serum level of fat - soluble vitamins among urban children in Zhejiang Province.METHODS： The serum level of fat-soluble vitamins was determined by RP- HPLC.RESULTS： Totally, 274 children were examined, and the average serum concentrations of vitamin E, vitamin A, and beta-carotene were（9.02±2.36）, （0.53±0.10） and （0.23 ± 0.16） μg·mL^-1, respectively. The detectable rate and mean of 25- hydroxyvitamin D3 were 75.55% and （18.51±7.64） ng·ml ^-1, rescpectively, and 51.10% and （20.83±10.67） ng·mL^-1 with vitamin D3.The serum level of fat-soluble vitamins was not significantly different between sexes（P 〉 0.05）, but significantly different between the clties（P 〈 0.01 or P 〈 0.05） . CONCLUSION：The serum level of vitamin E, vitamin A, and beta- carotene among urban children from the three cities of Zhejiang Province is good as a whole, but 25- hydroxyvitamin D3 and vitamin D3 is relatively poor.

关 键 词：脂溶性维生素 反相高效液相色谱法 血清 儿童 

分 类 号：R977.2[医药卫生—药品]