正常人与弱视患者图形视诱发电位的比较  

Comparison of VEP graphics between the patients with and without amblyopia

作　　者：曹春林[1] 田农[1] 潘丽娟[1] 

机构地区：[1]南京军区南京总医院眼科,210002

出　　处：《江苏医药》2007年第1期27-28,共2页Jiangsu Medical Journal

摘　　要：目的探讨图形视诱发电位(P-VEP)对弱视眼的临床应用价值。方法选择弱视眼重度17只眼、中度17只眼、轻度13只眼。P-VEP图形刺激采用棋盘翻转形式,频率2Hz,空间频率采用0·19、0·38、1·55周/度,对比度为90%。另选正常44只眼作为对照,比较两组的峰时与振幅。结果与正常对照组相比,弱视眼在0·19、0·38、1·55三种空间频率P100峰时明显延迟,而振幅未见明显改变;但是重度弱视患者在最高空间频率时振幅与正常相比有所降低。结论应用P-VEP对弱视眼进行检测,可以判断弱视眼的视功能损害。Objective To compare the changes of peak time and amplitude of visual-evoked potential （VEP） graphics between the eyes with and without amblyopia. Methods We observed 47 eyes of 17 severe, 17 moderate and 13 mild amblyopia with pattern reversal VEP （P-VEP） （a frequence of 2 Hz, spatial frequencies of 0. 19, 0. 38 and 1.55 cycles/degree, and a contrast of 90%）. The peak time and amplitude were compared between two groups. Results Compared with the controls, amblyopic eyes had a significant delay in P100 peak time at all three spatial frequencies. Although there was no significant difference in the amplitude between two groups group, the patients with severe amblyopia showed a decrease in amplitude at the highest spatial frequency （1.55 cycles/ degree） compared with control subjects.Conclusion Visual damage in amblyopic patients can be detected by the changes in P-VEP.

关 键 词：视诱发电位 峰时 振幅 

分 类 号：R477[医药卫生—护理学]