肺结核患者血清白细胞介素－2及可溶性白细胞介素－2受体的研究  

Study of serum interleukin-2 and soluble interleukin-2 receptor in patients with pulmonary tuberculosis

作　　者：王火[1] 谢立群[1] 王建芳 冀 

机构地区：[1]武警医学院内科教研室

出　　处：《武警医学》1996年第6期313-314,共2页Medical Journal of the Chinese People's Armed Police Force

摘　　要：为探讨白细胞介素－２（ＩＬ－２）、可溶性白细胞介素－２受体（ｓＩＬ－２Ｒ）在肺结核发生发展中的作用，采用酶联免疫吸附法（ＥＬＩＳＡ）检测５０例肺结核患者血清ＩＬ－２、ｓＩＬ－２Ｒ水平的变化。结果：进展期肺结核患者ＩＬ－２明显降低，ｓＩＬ－２Ｒ明显增高，与对照组相比统计学差异有显著性意义（Ｐ＜０．０１）。提示：ＩＬ－２。To evaluate the function of interleukin-2(IL-2)and soluble interleukin-2 receptor(sIL-2R )in development of pulmonary tuberculosis ,the levels of serum IL-2 and sIL-2R were detected in 50 patients with pulmonary tuberculosis using enzyme linked immunosorbent assay(ELISA)method. The results showed that the level of IL-2 was significantly decreased while sIL-2R was increased in developing stage of pulmonary tuberculosis . There is statistically significant difference as compared with the control group(P<0. o1). It is indicated that the changes of IL-2 and sIL.2R are related to the condition and prognosis of patients with pulmonary tuberculosis.

关 键 词：肺结核 白细胞介素2 受体 

分 类 号：R521.03[医药卫生—内科学]