壳聚糖季铵盐的制备及其抗菌性  

Preparation and Antibacterial Effect of Quaternary Ammonium Salt of Chitosan

作　　者：刘振儒[1] 赵江霞[1] 

机构地区：[1]青岛科技大学环境与安全工程学院,山东青岛266042

出　　处：《青岛科技大学学报（自然科学版）》2006年第6期509-511,共3页Journal of Qingdao University of Science and Technology:Natural Science Edition

摘　　要：用壳聚糖与碘甲烷、氢氧化钠直接合成了N-碘化三甲基壳聚糖季铵盐(TMCI),合成路线简单,成本低。对其抗菌性能的研究结果表明,该壳聚糖季铵盐具有良好的水溶性,抗菌性能优于羧甲基壳聚糖,对金黄色葡萄球菌最小抑菌浓度(MIC)为1.0 mg.mL-1,对大肠杆菌和白色念珠菌的最小抑菌浓度为1.25 mg.mL-1。A quaternary ammonium salt of chitosan（TMCI）was synthesized and its antibacterial activity was studied. It was showed that the TMCI was water soluble, had better antibacterial effect than CMC. The MIC of TMCI to S. aureuswas 1.0 mg · mL^-1 , to E. coli and C. albicans were 1.25 mg · mL^-1.

关 键 词：壳聚糖 壳聚糖季铵盐 羧甲基壳聚糖 抗菌性 

分 类 号：TQ53[化学工程—煤化学工程]