妊娠高血压综合征患者外周血P-选择素的表达  

The significance of P-selectin in patients with pregnancy induced hypertension

作　　者：王玉美[1] 

机构地区：[1]曲阜市人民医院妇产科,山东省曲阜273100

出　　处：《中国基层医药》2006年第12期2013-2014,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的探讨妊娠高血压综合征患者外周血P-选择素的表达与意义。方法用流式细胞术检测30例妊娠高血压综合征患者、20例正常妊娠者与15例正常人外周血P-选择素表达。结果妊娠高血压综合征患者外周血P-选择素表达为(18.63±8.92)%,明显高于正常妊娠组(3.25±1.73)%(P<0.01)和正常对照组(2.78±1.04)%(P<0.01)。结论妊娠高血压综合征患者存在P-选择素的高度表达。Objective To explore the significance of P-selectin expressed in circulating blood in patients with pregnancy induced hypertension（PIH）. Methods The expression of P-selectin were detected by flow cytometry in 30 PIH patients,20 normal pregnant patients and 15 normal controls. Results The level of P-selectin in PIH patients （ 18.63±8.92） % was significantly higher than that of normal pregnant group （3.25±1.73） % （ P〈0.01 ） and that of control group （2.78±1.04） % （ P〈0.01 ）. Conclusion The active PIH patients have highly-expressed P-selectin in circulating blood.

关 键 词：妊娠并发症 心血管 高血压 P-选择素 

分 类 号：R714.246[医药卫生—妇产科学]