一种海绵状伤口敷料的制备及结构性能的研究  

作　　者：何兰珍[1] 杨丹[1] 刘毅[1] 

机构地区：[1]广东海洋大学理学院,524088

出　　处：《医药世界》2006年第12期59-60,共2页Medicine World

摘　　要：采用冷冻壳聚糖-明胶共混液诱导相分离的方法，制成多孔性、亲水性、透气性良好的海绵状伤口敷料。通过对海绵体敷料结构及性能的研究，结果表明：壳聚糖与明胶分子之间形成了较强的氢键，壳聚糖中的-NH2与明胶中的-COOH发生酰胺化反应，说明壳聚糖的羟基与交联剂之间有反应发生，其反应历程有待进一步研究。由此可认为两种物质达到分子水平的分散，具有良好的相容性。By freezing chitosan-gelatin complex induce phasic abruption, the porous and ventilative spong of chitosan-gelatin was made, and the spong of chitosan-gelatin was studied on its structure and performance. The result indicated that： There were strong hydrogen bonds formed between the molecules of chitosan and gelatin. The amidation reacted in -NH2 of chitosan and OOH of gelatin.Moreover, the chitosan Has Condensation reaction with the crosslinking agent . According to the above elaboration may think two kind of matter achieved the molecular level the disperser, they has the good compatibility.

关 键 词：壳聚糖 明胶 相分离 海绵状伤口敷料 

分 类 号：TQ436.5[化学工程]