脑多发性硬化临床治愈后MRI表现  

Findings of MRI in clinical cured cerebral multiple sclerosis

作　　者：卢占兴[1] 徐爱民[1] 陈锦州[1] 李晓[1] 

机构地区：[1]河南省平顶山煤业集团总医院放射科MRI室,河南平顶山467000

出　　处：《河南医学研究》2006年第4期349-351,共3页Henan Medical Research

摘　　要：目的:探讨脑多发性硬化(multiple sclerosis,MS)临床治愈后的MRI表现及其临床意义。方法:回顾性分析14例临床治愈后的脑MS病例的MRI表现。结果:14例MRI共发现病灶103个,增强扫描呈环状、条状和结节状强化。于治愈后第1、3、6个月随访,分别有1、3、5例临床症状再现。平扫复查MRI发现103个异常信号,增强复查异常对比强化程度有变化,强化程度的变化与临床症状再现呈正相关,统计学处理有显著性差异。结论:临床治愈后的脑子扫MRI图像上仍可见异常信号,增强扫描像上异常对比病灶强化程度的变化可作为评价临床疗效和预后指标。Objective： To investigate the findings of MRI in cerebral multiple sclerosis （MS） patients who have been cured use medicine and their clinical significance. Methods ： Review the findings of MRt in 14 cases with cerebral MS after they have been treated use of prednisone , their objective symptom disappear so called clinical cured. Results ： 103 focus are found in 14 cases with cerebral MS by MRI. Presents circle, strip and node enhancement after adminester gadolinium MRI. The follow-up has been made at 1,3,6 month respectively after impact treated with high dose methylprednisolone. Among the 14 cases, 1,3,5 patients＇ symptom reappear accordingly. The follow-up plain MRI find 103 lesion. The intensity of enhancement lesion changes, that show positive correlation to clinic symptom reappear. Conclusion： For cerebral MS patients who have been cured in clinical and their clinical syndrome is disappeared , but abnormal signal may also exist in their follow up plan scanning MRI. The intensity of enhancement lesion changes. It may be the standard on to evaluate the treatments efficiency and pregnoses.

关 键 词：多发性硬化 治疗 MRI 

分 类 号：R445.2[医药卫生—影像医学与核医学]