重型颅脑损伤患者甲状腺激素水平及其与预后的关系  

Relationship between Glasgow Coma Scale evaluation and levels of thyroid hormone in craniocerebral trauma patients

作　　者：林启明[1] 关国梁[1] 黄志雄[1] 

机构地区：[1]南方医科大学附属南海医院神经外科,广东佛山528200

出　　处：《医学信息（手术学分册）》2006年第5期11-13,共3页Medical Information Operations Sciences Fascicule

摘　　要：目的探讨颅脑损伤患者甲状腺激素水平与颅脑外伤程度和预后的关系。方法用放免法测定395例颅脑损伤患者的甲状腺激素水平并与疾病严重程度进行比较。结果GCS评分越低,TT3、TT4含量下降越明显;GCS评分与TT3、FT3含量均呈正相关(r_1=-0．506,r_2=- 0．434,P均＜0．05);重型颅脑损伤组TT3和FT3含量均低于对照组(P＜0．05);死亡组TT3和FT3的含量明显低于存活组(P＞0．05)。结论重型颅脑损伤患者病情越重,甲状腺激素水平下降幅度越大;TT3和FT3含量可作为评价颅脑损伤患者预后的指标。Objective To examine the relationship between the acute craniocerebral trauma evaluation Glasgow Coma Scale（GCS） score and levels of thyroid hormone. Methods GCS score was derived as described and the content of thyroid hormone was measured by radioimmunoassy （RIA） in 395 patients with craniocerebral trauma. Results The Iow- er the GCS score,the more the decreases in the content of triiodothyronine （TT3） and free triiodothyronine （FT3）. The content of TT3 and FT3 was positively related to GCS score （ r~ = - O. 506, G = - O. 434, P 〈 O. 05）. The content of TT3 and FT3 were obviously lower in the Serious craniocerebral trauma group than in the light craniocerebral trauma group （P〈 O. 05） and lower in the death group than in the surrival group（P〈0. 05）. Conclusions The content of TT3 and FT3 can predict the prognosis of craniocerebral trauma patients,

关 键 词：颅脑损伤 甲状腺激素 预后 

分 类 号：R459.7[医药卫生—急诊医学]