妊娠肝内胆汁淤积症对胎儿生长的影响  

The effect to fetal growth in intrahepatic cholestasis of pregnancy

作　　者：邵勇[1] 漆洪波[1] 张建华[1] 姚珍薇[1] 吴味辛[1] 

机构地区：[1]重庆医科大学附属第一医院妇产科,重庆400016

出　　处：《重庆医科大学学报》2007年第1期69-71,共3页Journal of Chongqing Medical University

基　　金：重庆医科大学优秀博士论文基金资助(No.2004-17)。

摘　　要：目的:探讨妊娠肝内胆汁淤积症(ICP)对胎儿生长的影响。方法:对1999年1月￣2003年12月共5年间在我院分娩的332例ICP孕妇的胎儿出生体重进行详细分析。结果:(1)ICP332例中,早产的发生率为29.2%,与正常对照组比较,差异有极显著性(P<0.01);小于胎龄儿(SGA)发生率为5.1%,与正常对照组比较,差异无显著性(P>0.05)。(2)ICP轻度组中小于胎龄儿(SGA)、适于胎龄儿(AGA)和大于胎龄儿(LGA)的构成比分别为3.4%、76.5%和20.7%,与ICP重度组比较,差异无显著性(P>0.05)。(3)ICP不同病程组SGA、AGA和LGA构成比差异无显著性(P>0.05)。结论:ICP孕妇无慢性胎盘功能不良,对胎儿生长无明显影响。Objective：To investigate the effect to fetal growth in intrahepatic cholestasis of pregnancy （ICP）.Method：The fetal birthweight of 332 cases ICP from January 1999 to December 2003 were analyzed carefully.Results： （1） In all 332 cases of ICP,the occurrence of preterm was 29.2% which was significantly higher than the normal control group,and the occurrence of Small for Gestational Age （SGA）was 5.1% which was no significant difference when compared to the normal control group.（2） There were 3.4%,76.5% and 20.7% cases of SGA,AGA and LGA in mild ICP group,respectively.No significant differences were found when compared to the constituent ratio of SGA,AGA and LGA between the mild and severe ICP group（3）There were no significant differences about the odds ratio of SGA,AGA and LGA in different courses of ICP.Conclusion：It demonstrated that no chronic placental dysfunction and no obvious effect to fetal growth in ICP.

关 键 词：妊娠并发症 胆汁淤积症 肝内 胎儿生长 

分 类 号：R714[医药卫生—妇产科学]