深吸气量的测定在慢性阻塞性肺疾病患者中的临床意义  

The clinical implication of inspiratory capacity in patients with chronic obstructive pulmonary disease

作　　者：耿爽[1] 杨炯[1] 余红缨[1] 

机构地区：[1]武汉大学人民医院呼吸内科,武汉430060

出　　处：《临床内科杂志》2007年第1期20-22,共3页Journal of Clinical Internal Medicine

摘　　要：目的探讨肺功能指标深吸气量的测定在慢性阻塞性肺疾病患者中的临床应用价值。方法对21例COPD患者肺功能测定和支气管舒张试验,比较吸入沙丁胺醇200μg前后各肺功能指标的变化,并比较各指标在支气管扩张试验阳性组与阴性组、阻塞程度较中度组与重一极重度组的组中和组间差异性。结果在各项肺功能指标中,仅IC、FVC和FEV1在吸药后增加,其中IC的增加幅度最大。舒张试验阳性组和阴性组IC皆明显增加,且增加幅度相似。IC的增加幅度在重—极重度组大于轻—中度组。结论IC的增加与舒张试验的阳性和阴性结果没有必然的关联,可作为独立指标。支气管扩张剂缓解呼吸困难症状和增加运动耐力的作用在阻塞程度较重者更明显。Objective To evaluate the clinical implication of inspiratory capacity, a pulmonary function index,in patients with chronic obstructive pulmonary disease. Methods We performed bronchodilator tests in 21 patients with chronic obstructive pulmonary disease, compared the variation of pulmonary function indexes before and after inhaling Salbutamo1200μg, compared their differences in and between the responder group and the nonrespender group to bronchodilator, and the differences in and between the mild-moderate group and the severe-exceeding severe group. Results In those pulmonary function indexes ,IC,FVC and FEV1 increased after inhaling Salbutamol. IC has the greatest variation rate. The increases of IC in the nonrespender group and the respeonder group were significant and similar. The increase of IC in the severe-exceedlng severe group was greater than in the mild-moderate group. Conclusion The increase of IC hasn＇t a certain relation with the result of bronchodilator test. The effects of bronchodilator to alleviate dyespoea and improve exercise tolerance are greater in the severer group.

关 键 词：深吸气量 肺功能 慢性阻塞性肺疾病 

分 类 号：R563.9[医药卫生—呼吸系统]