基层医院清洁手术抗菌药物应用与费用分析  

Application and cost analysis of antimicrobial agents in clean operation in basic-level hospitals

作　　者：张兴华[1] 徐凤霞[1] 孙洪芹[1] 田蕾[1] 吕艳华[1] 

机构地区：[1]潍坊市人民医院,山东潍坊261041

出　　处：《中国感染控制杂志》2007年第1期27-29,共3页Chinese Journal of Infection Control

摘　　要：目的了解基层医院清洁手术预防应用抗菌药物情况,规范抗菌药物的预防应用,降低医疗成本。方法设计统一调查表,调查某市13家县级医院2004年9月份清洁手术应用抗菌药物情况。结果共调查639例清洁手术患者,抗菌药物预防使用率为98.28%(628/639);抗菌药物平均使用时间为(7.60±2.57)d;单一用药占55.25%(347/628),联合用药占44.75%(281/628);用第三代头孢菌素以上及广谱抗菌药物者占50.64%(318/628);人均抗菌药物费用为人民币(1 064.64±286.51)元,占药品费用的43.38%,心胸外科、神经外科患者平均抗菌药物费用较高,分别为(2 783.10±653.39)元、(1 991.56±623.32)元。结论基层医院清洁手术抗菌药物预防使用率高,用药时间长、起点高等是不合理用药的主要表现,也是造成抗菌药物费用高的主要原因。Objective To investigate the application of prophylactic antimicrobial agents in clean operation, stand ardize the application of prophylactic antimicrobial agents and reduce the medical cost. Methods Application of antimicrohial agents in patients who received clean operations in 13 county-level hospitals in a city in september 2004 were investigated and filled in the questionnaires. Results Sixty hundred and thirty-nine patients were investigated, prophylactic antimicrobial usage rate was 98. 28% （628/639）, the average time for using antimicrobial agents was （7. 60 ± 2. 57）days, 55.25% （347/628）were for single usage, 44. 75%（281/628）for combined usage, 50. 64%（318/ 628） were third generation cephalosporins. Average cost of antimicrobial agents was （￥1 064. 64 ± 286. 51 ）, which accounting for 43. 38% of total drug expense, expenses of cardiothoracic surgery and neurosurgical department was higher, which was（￥2 783. 1 ± 653. 39） and （￥ 991.56 ± 623.32） respectively. Conclusion Antimicrobial prophylactic usage in basic-level hospitals is high, the main irrational drug use are long usage time and superior drug usage, which are also the main causes of high cost of antimierobial agents.

关 键 词：医院 县 清洁手术 抗菌药物 合理用药 成本及成本分析 

分 类 号：R969.3[医药卫生—药理学]