颅脑外科感染假单胞菌培养及其药敏分析  

Pseudomonas cultivation and analysis of drug sensitivity in neurocranial surgery

作　　者：郑定容[1] 周育瑾[2] 黄龙[1] 赖玉华[1] 

机构地区：[1]深圳市宝安区西乡人民医院检验科,518102 [2]深圳市宝安区西乡人民医院神经外科,518102

出　　处：《中国医师进修杂志（外科版）》2007年第1期42-43,45,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的研究颅脑外科感染假单胞菌培养及其药物敏感性（药敏）情况。方法调查经病原学检查所证实的医院感染病例56例：细菌鉴定采用由英国制造的细菌鉴定药敏仪；抗菌药物的药敏试验采用微量测定法。结果培养出的13株假单胞菌中铜绿假单胞菌6株，占46．15％；产碱假单胞菌6株，占46．15％；嗜麦芽窄食单胞菌1株。占7．69％。铜绿假单胞菌对亚胺堵南敏感率为83．33％；产碱假单胞菌对亚胺培南敏感率为66．67％。均对第三代头孢菌素和喹诺酮类有较高耐药率。结论颅脑外科感染假单胞菌是抢救危重患者的一个严重问题；细菌耐药和交叉耐药的日趋普遍是当前抗感染治疗的困难所在。Objective To analyze the results ofpseudomonas cultivation and drug sensitivity test in neurocranial surgery. Methods Morbidity of nosecomial infections was investigated and etiological examination was performed in 56 cases by bacteria identification and drug sensitivity analyser. The microestimation was adopted in susceptibility test. Results Among 13 strains of pathogens, pseudomonas aeruginesa, pseudomonas pseudoalcaligenes and stenotrophomo-nasmahophilia were 46.15% （6/13）, 46.15% （6/13）and 7.69% （1/13） respectively. The result of susceptibility test showed that pseudomonas aeruginesa was sensitive to imipenem （83.33%）, pseudomonas pseudoalcaligenes was sensitive to imipenem （66.67%）. The all bacteria showed a high resistance to the third generation cephalosporin and quinolones. Condusions Acquirecl infection of patients in neurecranial surgery is a severe problem encountered in treatment. Bacterial resistance or cross-resistance to antibiotics is more popular in neurocranial surgery, which is the difficulty of modern anti-infective treatment. Abuse of antibiotic is one of the important reasons of leading to resistance or cross-resistance to antibiotics.

关 键 词：颅脑外科 假单胞菌属 药物敏感性 

分 类 号：R378.991[医药卫生—病原生物学]