检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
机构地区:[1]福建医科大学附属协和医院内分泌科,福建省福州市350001
出 处:《中国现代医药杂志》2007年第1期49-51,共3页Modern Medicine Journal of China
摘 要:目的探讨肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)与2型糖尿病及其大血管并发症的关系。方法国内外许多学者通过放免法或ELISA法分别测定健康人群、2型糖尿病及合并大血管病变患者血浆TNF-α水平,并对结果进行严格的统计处理和分析。结果2型糖尿病患者TNF-α水平增加,合并大血管病变患者升高更明显。结论TNF-α作为一种炎症反应相关的细胞因子,通过不同途径参与胰岛素抵抗和大血管并发症的发生,可为糖尿病的预防和治疗提供新的研究方向。Objective To study the relativity between TNF-α and type 2 diabetic patients with macrovascular complications. Methods Many scolors in and abrord have investigated the TNF-α changes in type 2 diabetic patients with and without macrovascular .The plasma TNF-α levels was assayed through radioimmunoassay or ELISA and the results were coneluded through stricitly statistical analysis.Results The level of TN-αin type 2 diabetic patients with macrovascular complications was significantly higher than those without complications and even more in the normal controls ; the level of TNF-α in type 2 diabetic patients was higher than that in the normal controls. Conclusion Tumor necrosis factor-α is a cytokine closely associated with insulin resistance and macrovascular complications in type 2 diabetes.This will provide a new research field in the development of new preventive and therapeutic drugs for diabetes.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.200