长春市儿科感染性疾病抗生素使用现状分析  

Analysis on present status of antibiotic use in paediatrics'infectious diseases in Changchun city

作　　者：王国庆[1] 李凡[1] 

机构地区：[1]吉林大学基础医学院病原生物教研室,长春130021

出　　处：《中国公共卫生》2007年第2期138-139,共2页Chinese Journal of Public Health

基　　金：国家"十五"科技攻关计划项目课题(2004BA720A09-02)

摘　　要：目的了解长春市儿科感染性疾病抗生素的使用情况,为指导抗生素合理使用提供参考依据。方法随机抽取2003~2006年长春市1所三级甲等医院儿科因感染性疾病住院病例700例,调查抗生素联合使用情况、药品种类、使用频率、平均用药天数,分析抗生素使用与药敏试验和白细胞(WBC)计数的关系。结果2003~2006年,长春市儿科感染性疾病抗生素的使用率分别为95%,100%,99%,100%;各年使用频率最高的抗生素分别为头孢呋辛(37%)、头孢呋辛(32%)、头孢硫咪(25%)、头孢硫咪(33%);平均用药天数最多的抗生素分别为头孢呋辛(4.5d)、头孢呋辛(4.5d)、头孢噻肟/舒巴坦(4.7d)、头孢噻肟/舒巴坦(6.7d);药敏试验率分别为8.4%,12%,12.7%,11%;WBC计数在正常范围内(4×109/L^10×109/L)的抗生素使用率分别为54.2%,63%,67.7%,71%。结论长春市儿科感染性疾病抗生素用药单一,缺乏科学依据,抗生素使用需进一步规范。Objective To investigate the present status of antibiotic use in paediatries＇infectious diseases in Changchun and guide the rational use of antibiotics. Methods 700 eases of infectious diseases of childen from Changchun were randomly selected for a retro - spective investigation from 2003 to 2006. To analyze the combined treatment status, variety, frequency, average days of medication and the relationship between antibiotic use with susceptibility test and WBC. Results From 2003 to 2006, the rates of antibiotic use were 95 %, 100 %, 99 %, 100 %. The most use frequencies of antibiotic were eefuroxime （37 % ）, cefuroxime（32 % ）, cephathiamidin （25 % ）, cephathiamidin （33 % ）. The most days of antibiotic use were cefuroxime （4.5d）, cefuroxime（4.5d）, cefotaxim/sulbactam（4.7d）, cefotaxim/sulbactam （6.7d）. The rates of the antibiotic use within susceptibility test were 8.4%, 12%, 12.7%, 11%. The rates of the antibiotic use within normal limits of WBC were 54.2 %, 63 %, 67.7 %, 71%. Conclusion The antibiotic use of paediatrics＇ infectious diseases is unitary and irrationalitical in Changchun. The use of antibiotic needs more standardization.

关 键 词：儿科 抗生素 感染性疾病 

分 类 号：R915[医药卫生—微生物与生化药学]