儿童系统性红斑狼疮51例临床分析  

Clinical Analysis of 51 Cases of Systemic Lupus Erythematosus in Children

作　　者：熊小燕[1] 曾华松[1] 陈耀勇[2] 王蓓[1] 韦茹[1] 姚翠婵[1] 

机构地区：[1]广州医学院附属儿童医院过敏免疫风湿科,广东广州510120 [2]广州医学院实验医学研究中心,广东广州510182

出　　处：《广州医学院学报》2006年第5期32-35,共4页Academic Journal of Guangzhou Medical College

摘　　要：目的:总结儿童系统性红斑狼疮(SLE)的临床及实验室检查特点。方法:对本院51例住院患儿SLE的临床资料进行回顾性分析。结果:临床表现以肾损害(84.3%)、发热(70.6%)、皮疹(68.8%)、淋巴结肿大(41.2%)较常见。实验室检查以ANA(+)(92.0%)、补体降低(90.0%)、ESR升高(84.0%)、贫血(83.6%)较常见。病情活动性(SLEDAI积分)以轻至中度活动为主。结论:儿童SLE的临床表现多样化,应结合实验室检查进行分析,早期确诊,避免误诊,积极治疗。Objective： To summarize the clinical and laboratory features of systemic lupus erythematosus in 51 pediatric cases. Methods： The clinical data of 51 cases of systemic lupus erythematosus in children were analyzed retrospectively. Results： The common clinical manifestations were renal damage（ 84.3% ）, fever（70.6% ）, skin rash （68.8%） ,and enlarged lymph nodes（41.2% ）. The common laboratory findings included positive anti-ANA antibody （90.0%） , depressed complement level（90.0% ） , quickened ESR（ 84.0% ）andanaemia （83.6%）. Activity in disease （SLEDAI score）in the most cases were at mild to moderate levels. Conclusion：The clinical manifestations of systemic lupus erythematosus in children are diverse. It is necessary to analyze in combination with laboratory findings, in order to get a sound diagnosis and active treatment.

关 键 词：儿童 系统性红斑狼疮 临床特点 

分 类 号：R593.241[医药卫生—内科学]