小白鼠心阻抗微分图正常值分析  

DETERMINATION AND ANALYSIS OF HEART FUNCTION BY IMPEDANCE CARDIOGRAPHY IN MICE

作　　者：解绍玢 白凤菊 娄建石 

机构地区：[1]天津护士学校药理教研室

出　　处：《天津医科大学学报》1996年第4期7-9,共3页Journal of Tianjin Medical University

基　　金：国家自然科学基金

摘　　要：本文采用阻抗法无创性心功能血流动力学计算机实时监测系统，对３０只小鼠的心功能进行了测定。其心阻抗微分图的Ａ、Ｃ、Ｏ波明显，且均与心电图（ＥＣＧ）的Ｐ波、ＱＲＳ波、Ｔ波在时间上相对应。获得了麻醉小鼠的心功能参数，其中心率（ＨＲ）为５５２．４７±８０．７３ｂｅａｔ／ｍｉｎ，射血前期（ＰＥＰ）为２５．８６±４．８０ｍｓ，左室射血期（ＬＶＥＴ）为５８．８３±９．１３ｍｓ，心输出量（ＣＯ）为２．５０±０．８８ｍｌ／ｍｉｎ，心脏指数（ＨＩ）为４６６．７６±１８６．６１ｏｈｍ／ｓ２。雌雄间差异不明显。The heart function were determined by impedance caridiography with non invasive heart function and hemodynamic computer monitoring system in 30 mice under intraperitoneal sodium pentobarbital anesthesia.The C,A,and C waves which appeared clearly in impedance cardiography paralleled and responded the P,QRS and T waves in ECG.The results showed that the HR was 552 5±80 7 beat/min,PEP 25 86±4 80ms,LVET 58 83±9 13ms,CO 2 50±0 88ml/min,HI 464 8±186 6 ohm/s 2。The difference was not found between male and female mice,but found among mice,rats,rabbits and other species.

关 键 词：心功能 心阻抗 药理学 实验方法 

分 类 号：R965.2[医药卫生—药理学]