广东省雷州市鼠疫疫源地人群血清流行病学调查及分析  

Investigation of serum epidemiology from the plague foci population in Leizhou island,Guangdong

作　　者：张涛 夏连续[2] 梁秋光 海荣[2] 徐冬蕾[2] 杨华源 俞东征[2] 

机构地区：[1]广东省湛江鼠疫防治研究所,湛江524037 [2]中国疾病预防控制中心传染病控制所

出　　处：《中国地方病防治》2007年第1期16-18,共3页Chinese Journal of Control of Endemic Diseases

基　　金：广东省医学科技资金项目(A2005737)

摘　　要：目的了解广东省鼠疫疫源地健康人群鼠疫FI抗体的分布水平,及其产生和维持机制。方法采集雷州市鼠疫疫源地2个乡镇农民的血样121份作为调查组和非历史疫区的农民血样200份作为对照组,进行常规鼠疫间接血凝试验。结果通过对鼠疫疫源地人群的121份血清的检测.共检出鼠疫FI抗体阳性血清12份,阳性率为9.91%%。鼠疫非疫区健康人群血清200份,结果均为阴性。结论在鼠疫疫源地50岁以上健康人群中存在着一定比例FI抗体阳性者,是鼠疫菌苗被动免疫产生,还是50年前隐性鼠疫感染等因素,有待进一步调查和研究,但排除阳性人群居住区域有动物鼠疫现疫流行的存在。Objective To explore the distribute of plague FI - antibody positive people from plague fool population in Leizhou island . Methods The serum samples from 121 people in Leizhou island plague foci and 200 people in the non - plagued foci area were routinely detected by indirect hemagglutination （ IliA ）. Results 12 samples were positive of plague FI antibody in 121 serum samples from the plague foci is Leizhou island ,the positive rate being 9.91% ,200 serum samples of healthy people from non - plagued loci were all negative. Conclusions Serum FI - antibody positive people are popular in the plague foci ,at over the age of 50 old . Which is it , plague - vaccinated or the hidden infected before 50 years. There is no doubt it was local animate plague that are not prevalent in the areas of serum FI -antibody positive people ,especially in recent years.

关 键 词：鼠疫 FI抗体 被动免疫 隐性感染 

分 类 号：R516.8[医药卫生—内科学]