三七镇痛膏质量标准的研究  

Study on quality Standard for Sanqi Zhentong Cream

作　　者：干国平[1] 江维[1] 张义生[2] 刘焱文[1] 

机构地区：[1]湖北中医学院药学院,湖北武汉430065 [2]武汉市中医院,湖北武汉430014

出　　处：《湖北中医学院学报》2006年第4期25-26,共2页Journal of Hubei College of Traditional Chinese Medicine

摘　　要：目的建立三七镇痛膏的质量控制方法。方法采用显微鉴别法和TLC法鉴别红花、穿山甲、威灵仙、牛膝、海马、葛根、川芎、三七等药;采用HPLC法测定人参皂苷Rgl的含量,HyPersilC-18(4.6mm×250mm,7μm),流动相:乙腈-0.05%H3PO4(30:70),流速1.0ml.min-1,检测波长203nm。结果本法鉴定效果较好,阴性对照无干扰;人参皂苷Rgl平均加样回收率为98.3%,RSD为2.04%,n=6。结论本法可以控制制剂质量。Objective：To establish the standard of Sanqi Zhentong cream. Methods.Flos carthami, Squama manitis, Radix clematidis,Radix achyranthis bidentatae, Hippocampus, Radix puerariae, Rhizoma ligustici Chuanxiong were identified by microscope or TLC, Gensenoside Rgl was determined by HPLC on Hypersil C-18 column（250mm×4.6mm,7μm） ,using with a mobile phase of acetonitrile-0. 05% H3 PO4（30 ： 70）, the flow rate was at 1.0ml/min; the detection wavelength was 203nm. Results：The identify methods were available, and not to be disturbed by blank sample;the average recoveries was 98. 3 %, RSD was 2.04 % （n= 6）. Conclusion： The methods are suitable for the quality control of the cream.

关 键 词：三七镇痛膏 HPLC 人参皂苷RGL 

分 类 号：R283.6[医药卫生—中药学]