胃内注入凝血酶治疗新生儿窒息后急性胃粘膜出血  

Observation of the curative effect of thrombin injected into stomach to treat neonates with acute stomach mucous membrane bleeding after suffocation

作　　者：马香桃[1] 

机构地区：[1]河南省安阳市第三人民医院,河南安阳455000

出　　处：《儿科药学杂志》2007年第1期43-44,共2页Journal of Pediatric Pharmacy

摘　　要：目的：探讨胃管内注入凝血酶治疗新生儿窒息后胃粘膜出血的疗效。方法：将62例新生儿窒息后胃粘膜出血患儿随机分为对照组28例和观察组34例，观察组在常规洗胃后将凝血酶500U溶于3．5mL生理盐水中经胃管注入胃内，每8h-次，至胃内出血停止。结果：观察组总有效率97．1％，对照组总有效率75．0％（P〈0．05）。结论：胃内注入凝血酶对新生儿窒息后急性胃粘膜出血有较好的治疗作用。Objective： To probe into the curative effect of thromhin injected into stomach to treat neonates with stomach mucous membrane bleeding after suffocation. Methods： 62 infants with stomach mucous membrane bleeding after suffocation were divided at random into a control group of 28 and a treatment group of 34 with 500 u thrombin dissolved into 3 -5 mL physiologicaf saline injected into the stomach after washing the stomach in routine, once very 8 hours until the haemorrhage stopped. Results： The total curative effect of the treatment group was 33/34 （97.1% ）, while that of the control group was 21/28 （75 % ）, which had significant differences （P 〈 0. 05）. Conclusions： Thrombin injected into the stomach has a good curative effect in the treatment of neonates with acute bleeding in mucous membrane of stomach after suffocating.

关 键 词：凝血酶 新生儿 窒息 胃粘膜出血 

分 类 号：R722.152[医药卫生—儿科]