丹参注射液联合依地酸钙钠注射液治疗职业性铅中毒临床观察  

Clinical Observation of Occupation Lead Poisoning Treated with Danshen Injection Combined with Calcium Disodium Chelate

作　　者：郑红[1] 伍健芝[1] 郑刚[1] 范荣[1] 

机构地区：[1]广东省职业病防治院,广州市510300

出　　处：《中国药房》2007年第5期356-357,共2页China Pharmacy

摘　　要：目的观察丹参注射液联合依地酸钙钠注射液治疗职业性铅中毒的疗效。方法305例职业性铅中毒患者随机分为联合治疗组(160例)与对照组(145例),分别给予丹参注射液联合依地酸钙钠注射液、单用依地酸钙钠注射液治疗,每周连续用药3d,停4d为1个疗程。观察2组24h尿铅含量恢复至正常所需疗程。结果联合治疗组与对照组的尿铅至正常所需疗程分别为2.89、4.01(P<0.05)。结论丹参注射液联合依地酸钙钠注射液治疗职业性铅中毒疗效更佳。OBJECTIVE：To investigate the clinical efficacy of Danshen injection in treatment of occupation lead poisoning in combination with calcium disodium chelate. METHODS： 305 occupation lead poisoning patients were randomly divided into the treatment group （n = 160） and control group （n = 145）.The treatment group was given Danshen injection combined with calcium disodium chelate while the controlled group was given Calcium disodium chelate alone. The medicine administration continuously lasted for 3 d with intervals of 4 d,which was 1 course of treatment. Observe the two groups until the content of lead in urine of 24 hours recovers to the normal level and record the time needed. RESULTS： The needed course for the treatment group was 2.89, while that for the control group was 4.01（P〈0.05） .CONCLUSION： The efficacy of Danshen injection combined with Calcium disodium chelate is better than the efficacy of treatment with calcium disodium chelate alone.

关 键 词：丹参注射液 依地酸钙钠注射液 职业性铅中毒 

分 类 号：R979.3[医药卫生—药品]