氟西汀对伴抑郁状态心血管疾病患者的疗效观察  

Efficacy of Fluoxetine in Treatment of depression with Cardiovascular Patients

作　　者：古筱茹[1] 徐宁[1] 梁健球[1] 黄永光[1] 

机构地区：[1]佛山市第二人民医院,广东佛山528000

出　　处：《国际医药卫生导报》2007年第2期60-62,共3页International Medicine and Health Guidance News

摘　　要：目的探讨伴抑郁状态心血管疾病患者的临床特征和氟西汀的临床疗效。方法对2004年7月-12月在我院住院的560例患者进行随机抽样调查，随机抽取240例患者采用抑郁自评量表（SDS）进行评分，分析伴抑郁状态心血管疾病患者的比例和临床特征对伴抑郁状态心血管疾病患者的予以分组治疗；观察组单纯使用心血管药物，治疗组合用口服氟西汀治疗，比较分析两组治疗效果。蛄果伴抑郁状态心血管疾病患者占抽样调查心血管疾病患者的20．8％；该类患者除了其相应心血管疾病的症状外，常表现为主诉多，难以缓解的胸闷、胸痛、气促和心悸等症状，血压波动大；治疗的耐受性和依从性差，单纯使用心血管药物治疗效果欠佳，合并使用抗抑郁药物氟西汀治疗疗效显著（P〈0．001）。蛄论抑郁状态在心血管疾病患者中占有很高的比例，对此类患者的主诉应加以分析，注意识别其类似于心血管疾病的躯体化症状；对此类患者在治疗心血管疾病的同时，应联合予以抗抑郁的药物。Objective To study the proportion, clinical characteristics and treatment of depression in cardiovascular patients. Methods 240 patients sampled randomly from 560 patients hospitalized in our department from July to Decemble in 2004 were graded by SDS. The proportion, clinical characteristics and treatment of depression in cardiovascular patients were studied. Result 20.8% of cardiovascular patients was complicated with depression. Besides the symptoms corresponded to cardiovascular disease, this section of cardiovascular patients have more complaining and particular symptoms, such as angina pectoris, arrhythmias and left heart failure difficult to relieved. They responded badly to only routine cardiovascular drug treatment. Additional administration of antidepressant drug and mental therapy were effective. Conclusion The proportion of depression in cardiovascular patients is very high. We should identify the symptoms of depression carefully,which is similar to cardiac disease. It is important to administrate antidepressant drug and mental therapy in the treatment of cardiovascular patients with depression.

关 键 词：抑郁状态 心血管疾病 抗抑郁治疗 

分 类 号：R54[医药卫生—心血管疾病] R74[医药卫生—内科学]