慢性浅表性胃炎中医证型与胃黏膜保护因子的相关性分析  

Relationship Analysis Between Chinese Medical Typing of Chronic Superficial Gastritis and Protective Factor

作　　者：刘卫红[1] 李萍[1] 张蕾[1] 王丽华[1] 于凤华[1] 

机构地区：[1]北京市中医研究所,北京100010

出　　处：《中华中医药学刊》2007年第2期285-287,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：北京市自然科学基金资助项目(7032014)

摘　　要：目的:探讨胃黏膜保护因子一氧化氮(NO)、超氧化物歧化酶(SOD)和前列腺素E2(PGE2)在慢性浅表性胃炎中医证型间的变化规律。方法:采用放免和比色法检测93例慢性浅表性胃炎患者(肝胃不和型60例、脾胃湿热7例、肝郁脾虚6例、脾胃虚弱7例、胃阴不足13例)血清及胃黏膜组织中NO、SDO及PGE2均低于单纯型浅表性胃炎。不同证型NO、SOD及PGE2含量较高。结论:不同证型慢性胃炎患者NO、SOD及PGE2的水平具有显著性差异,可能是不同证候的病理学基础,具有重要的临床参考价值。Objective ：To investigate the possible role of protective factor NO, SOD and PGE2 release of chronic superficial gastritis with different types according to the traditional Chinese medicine. Methods：NO,SOD and PGE2 in serum and mucosal tissues of the 93 patients with chronic superficial gastritis were detected by RIA method. Results ：The activities of NO,SOD and PGE2 were lower of patients with hemorrhagic, erosion and countercurrent chronic superficial gastritis than that of simplex gastritis. The activities of NO,SOD and PGE2 wera lower of patients with Weiyinxu,Piweixu and Gan - wei incoordination than those with Piweishire and Ganyupisu. Conclusion ： Protective factor NO, SOD and PGE2 release may play an important role in the pathogenesis of chronic superficial gastritis with different types according to the traditional Chinese medicine.

关 键 词：慢性浅表性胃炎 中医证型 保护因子 

分 类 号：R259.733.1[医药卫生—中西医结合]