益肾法治疗代谢综合征痰瘀证  

Clinical Research of Reinforcing Kidney Decoction for Metabolic Syndrome of Phlegm-Blood Stasis Due to Kidney Deficiency

作　　者：李晓政[1] 闫彩香[2] 

机构地区：[1]太原市第二人民医院,山西太原030002 [2]山西医科大学第二医院,山西太原030001

出　　处：《中国中医药信息杂志》2007年第2期19-20,82,共3页Chinese Journal of Information on Traditional Chinese Medicine

摘　　要：目的从肾立论探索益肾法治疗代谢综合征痰瘀证临床疗效。方法代谢综合征诊断标准执行中国代谢综合征建议诊断标准。证候诊断标准和症状分级标准采用中西医结合糖尿病诊疗标准(草案)。采用两相关样本六组的研究方法,42例符合纳入标准自愿口服中药者,男26例,女16例,年龄39～60岁,平均年龄46.4岁。均匀分为代谢综合征组和糖尿病组。纳入病例无严重的合并症和并发疾病。观察指标:证候积分、症状积分、血糖、血脂、血尿酸。结果代谢综合征组显效14例,有效5例,无效2例;2型糖尿病组显效8例,有效11例,无效2例。2组症状改善以头晕目眩和肢体沉重改善最为显著,观察指标改变率多元方差检验Hotelling's Trace,F=16.51,P=0.00。指标改善依次递减顺序为高密度脂蛋白、血尿酸、三酰甘油;收缩压和舒张压下降率表现出相似的水平。结论从肾立论治疗代谢综合征痰瘀证可以获得较好的症状、证候和指标疗效。Objective To study the clinical efficacy of Reinforcing Kidney Decoction for the treatment of metabolic syndrome diagnosed as traditional Chinese medicine （TCM） syndrome of phlegm-blood stasis due to kidney deficiency. Method 42 recipients who volunteered to accept the TCM therapy were up to the inclusion criteria and finally fulfilled this study. Of all the cases, there were 26 males and 16 females, their old years ranged from 39 to 60, which were divided into obesity type diabetics group and metabolic syndrome group, both of which were treated with oral Reinforcing Kidney Decoction combined with western medicine therapy, with a course of 4 weeks. The changes of clinical symptoms, body weight index （BMI）, fasting blood glucose （FBG）, 2 h post prandial glucose （2hFBG）, total cholesterol （TC）, triglycerides （TG）, high-density lipoprotein （HDL-C） levels, and serum uric acid were analyzed. Results Therapeutic effect in two groups ranked as significant, general and null effect, 14/5/2 vs 8/11/2, respectively. Dimness and heaviness feeling of limbs have been improved. Rate of syndrome scores and laboratory parameters descended great significant, Hotelling＇s Trace, F= 16.51, P=0.00. Compared with pretreatment, the levels of TC, TG, SUA obviously descended （P〈0.00）, and HDL-C ascended （P〈0.00）. There was no significant differences in BMI. Conclusion Reinforcing kidney can acquire therapeutic effect of metabolic syndrome TCM syndrome of phlegm-blood stasis due to kidney deficiency.

关 键 词：益肾法 代谢综合征 痰瘀证 糖尿病 

分 类 号：R442.8[医药卫生—诊断学]