HPLC-ELSD法测定麦冬药材及其提取物中果糖的含量  

Determination of Fructose in Radix Ophiopogonis and Extracts of Radix Ophiopogonis by HPLC-ELSD

作　　者：王志斌[1] 陈有根[1] 李慧[2] 

机构地区：[1]北京市药品检验所,北京100035 [2]中国中医科学院中药研究所,北京100700

出　　处：《中国中医药信息杂志》2007年第2期47-48,共2页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：科技部"十五"国家重大科技专项"创新药物和中药现代化"专题(2001BA701A36-2)

摘　　要：目的测定不同产地的川麦冬、浙麦冬药材及麦冬提取物中果糖的含量,为麦冬药材及其提取物的质量控制提供科学依据。方法采用HPLC-ELSD法测定麦冬药材及提取物中果糖的含量。结果川麦冬和浙麦冬药材中果糖的含量分别为11.32%～19.96%、3.85%～10.19%,川麦冬和浙麦冬提取物中果糖的含量分别为23.48%～25.82%、21.39%～23.29%。结论川麦冬药材中果糖的含量明显高于浙麦冬药材,川麦冬提取物中果糖含量与浙麦冬提取物基本一致。Objective To determine the content of fructose in radix ophiopogonis cropped in Sichuan and Zhejian, and in extracts of radix ophiopogonis. Methods A HPLC-ELSD method was used for determining the content of fructose. Results The content of fructose in radix ophiopogonis cropped in Sichuan and Zhejiang were 11.32%-19.96% and 3.85%-10.19%, respectively. The contents of fructose in extracts of radix ophiopogonis cropped in Sichuan and Zhejiang were 23.48% - 25.82% and 21.39% -23.29%, respectively. Conclusion The content of fructose in radix ophiopogonis cropped in Sichuan was higher than that of in Zhejiang. The content of fructose in extracts of radix ophiopogonis cropped in Sichuan was almost the same as that of in Zhejiang.

关 键 词：麦冬 麦冬提取物 果糖 含量测定 

分 类 号：R284.1[医药卫生—中药学]