大孔吸附树脂精制复方补肾生精胶囊的工艺研究  

Study on Refine Technics of Fufang Bushenshengjing Capsule with Macroporous Resin

作　　者：刘永[1] 荆海英[1] 郭立玮[1] 陈峰[1] 

机构地区：[1]南京中医药大学植物药深加工工程中心,江苏南京210029

出　　处：《中国中医药信息杂志》2007年第2期49-51,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家中医药管理局重点项目(97Z023)

摘　　要：目的探讨复方补肾生精胶囊中制首乌和淫羊藿的指标性成分二苯乙烯苷和淫羊藿苷的提取纯化工艺。方法对NKA-9、AB-8、D101、X-5、DM1305种树脂进行筛选,考察上样浓度、树脂用量、药液pH及洗脱剂的乙醇浓度和用量。结果采用AB-8树脂,上样浓度为原料药0.3g/mL,树脂用量为2mL/g原药材,不调药液pH,以5倍原药材量的70%乙醇洗脱。结论本实验为从复方补肾生精胶囊提取有效成分的工业化生产提供借鉴。Objective To study on purication of stilbene glycoside and icarrin with macroporous resin of radix polygoni multiflori praeparata cure succo glycines sotae and herba epimedii of Fufang Bushenshengjing Capsule. Methods To select the best type of resin from NKA-9, AB-8, D101, X-5 and DM130, to observe the factor of the concentration of water-extraction, the volume of resin, pH of water-extraction, the concentration and volume of ethanol. Results Using AB-8 resin, the concentration of water-extraction is 0.3 g/mL, the volume of resin （mL） to the mass of medicinal materials is 2, pH of water-extraction need＇t change, eluant is 70% ethanol and its volume （mL） is 5 times of the mass of medicinal materials （g）. Conclusion This research can provide reference for the extraction of active component from Fufang Bushenshengjing capsule in industrial production.

关 键 词：复方补肾生精胶囊 二苯乙烯苷 淫羊藿苷 大孔吸附树脂 

分 类 号：R283.5[医药卫生—中药学]