各向异性骨再造过程的实现  

Realization of Anisotropic Bone Remodelling Process

作　　者：马宗民[1] 李淑娴[2] 朱兴华[3] 

机构地区：[1]大连大学生物医学工程研究所,辽宁大连116021 [2]大连大学院士创业园,辽宁大连116622 [3]吉林大学工程力学系,吉林长春130025

出　　处：《航天医学与医学工程》2007年第1期28-31,共4页Space Medicine & Medical Engineering

基　　金：国家自然科学基金项目(10372034);大连大学科技发展基金项目

摘　　要：目的建立符合各向异性骨再造过程的骨再造理论模型,实现各向异性骨再造过程。方法基于Wolff定律及骨各向异性的力学性质,在仔细研究当前各向同性骨结构再造预测技术的基础上,将材料方向和主应力方向趋于一致作为骨再造平衡条件,提出新型各向异性骨再造模型,并以二维简支梁结构为例进行模拟。结果得到了二维简支梁结构的密度分布结果与主应力方向迹线图,并与各向同性模拟结果进行了对照,显示本模型模拟结果较为合理。结论新型各向异性骨再造模型,量化了骨再造过程和骨力学性质的各向异性,实现了骨再造过程的各向异性,应用该模型可进行更为准确的骨结构再造预测。Objective To develop a new theoretical model of bone remodelling to simulate and to realize the anisotropic bone remodelling process. Methods A new theoretical model of anisotropic bone remodelling was put forward on the basis of Wolff＇s law and anisotropic mechanical properties of bone after the current isotropic bone structure remodelling technology was studied in detail. The new model regarded an inclination for material orientation to be consistent with principal stress orientation as bone remodelling balance condition. The model was then applied to study the two-dimension simple supported beam. Results Simulation results of the two-dimension simple supported beam, density distributing figure and trace figure of principal stress orientation were obtained. In comparison with the simulation result of the isotropic model, the simulation result of the new model is more reasonable. Conclusion The new model quantitates the anisotropy of bone remodelling process and bone mechanical properties and then realizes the anisotropy of bone remodelling process. The model can be applied to even more exact bone structure forecast.

关 键 词：Wolff定律 各向异性 骨再造 骨力学性质 

分 类 号：R318.01[医药卫生—生物医学工程]