西藏藏族DYS287位点多态性研究  

Polymorphisms of DYS287 locus in Tibetans in Tibet

作　　者：文普帅[1] 温有锋[1] 席焕久[1] 任甫[1] 高静[1] 

机构地区：[1]辽宁医学院人类学研究所,锦州121001

出　　处：《武警医学》2007年第2期89-90,共2页Medical Journal of the Chinese People's Armed Police Force

基　　金：国家自然科学基金项目(NO.30570977)

摘　　要：目的以西藏拉萨、那曲地区藏族男性个体为研究对象,研究两地区男性Y染色体DYS287位点多态性。方法利用PCR结合琼脂糖凝胶电泳检测方法对105例藏族男性样本(其中拉萨41例,那曲64例)DYS287位点多态性进行分析。结果两地区人群均发现Alu插入阳性个体(即YAP阳性个体),拉萨、那曲YAP阳性率分别为41.5%和62.5%。结论DYS287位点是一个重要、稳定的遗传标记,YAP阳性率在不同地区的同一民族中存在差异,这可能是人群间基因交流的结果。Objective To study the polymorphisms of DYS287 locus of male Tibetans in Lhasa and Nagqu 64 in Tibet.Methods The polymorphisms of DYS287 locus in male 105 Tibetans （41 in Lhasa and Individuals Nagqu）were analyzed by PCR and agarose gel electrophoresis.Results withYAP ＋ were found in both areas,and YAP ＋ frequencies in Lhasa and Nagqu were 41.5% and 62.5% ,respectively. Conclusions DYS287 locus is an important and stable genetic marker,difference in YAP ＋ frequenciy in the same nationalffy in may result from gene exchange between human groups.

关 键 词：藏族 DYS287 多态性 

分 类 号：Q986[生物学—人类学]