应变率成像技术评价冠心病患者左室局部收缩功能异常  

Strain Rate Imaging for Quantitative Analysis of Regional Left Ventricular Systolic Dysfunction in Patients with Coronary Artery Disease

作　　者：邱琼[1] 杨莉[1] 伍卫[1] 刘英梅[1] 张小玲[1] 曹珊珊[1] 

机构地区：[1]中山大学附属第二医院心内科,广州市510120

出　　处：《中国超声医学杂志》2007年第2期119-121,共3页Chinese Journal of Ultrasound in Medicine

摘　　要：目的应用应变率成像(SRI)技术定量分析并比较心绞痛与心肌梗死(心梗)患者缺血与梗死心肌收缩期应变(ε)和应变率(SR)变化,探讨其评价冠心病患者左室局部收缩功能异常的价值。方法冠心病心绞痛组11例、心梗组21例,对照组20例。分别测量缺血、梗死和正常心肌的收缩期应变率(SRsys)、收缩期应变(εsys)和最大应变(εmax)。结果缺血、梗死心肌的SRsys、εsys和εmax的绝对值均显著低于正常心肌(P<0.01);梗死心肌较缺血心肌SRsys、εsys和εmax的绝对值降低更加明显(P<0.05)。结论SRI测得SRsys、εsys和εmax可定量评价冠心病患者左室局部收缩功能异常,并且有助于区分缺血与梗死心肌。Objective To detect and compare the longitudinal systolic strain rate （SR） and strain （e） of the infarcted and ischemic myocardium using strain rate imaging （SRI）, in order to explore the clinical value of SRI in evaluating regional left ventricular systolic dysfunction in patients with coronary artery disease. Methods Twentyone patients with myocardium infarction, 11 patients with angina pectoris and 20 healthy subjects were studied. Systolic SR （SRsys）,systolic ε （εsys） and maximum ε（εmax） from infarcted, ischemic and normal myocardium were analyzed. Results SRsys, εsys and εmax were decreased significantly in infarcted and ischemic segments （P〈0.01 ） . Compared with the ischemic segments, SRsys, εsys, εmax were decreased significantly in infarcted segments （P〈0. 05） . Conclusions SRsys, εand εmax measured by SRI can be used to quantitatively analyze regional left ventricular systolic dysfunction in patients with coronary artery disease , and aid in differentiating infarcted from ischemic myocardium.

关 键 词：应变率成像 超声心动描记术 冠心病 左室收缩功能 

分 类 号：R541.4[医药卫生—心血管疾病]