邻苯二酚的高效液相色谱分析  

High-Performance Liquid Chromatographic Analysis of Catechol Product

作　　者：邓国才[1] 徐莉[1] 刘歆颖[1] 穆瑞才[1] 刘智[1] 高力[1] 马洪涛[1] 李庆刚[1] 刘靖疆[1] 陈荣悌[1] 

机构地区：[1]南开大学化学系,天津300071

出　　处：《分析化学》1996年第11期1312-1315,共4页Chinese Journal of Analytical Chemistry

摘　　要：本文提出了邻苯二酚成品质量的高效液相色谱分析方法。采用硅胶柱：以正己烷－异丙醇－醋酸力流动相，梯度淋洗，实现了邻苯二酚、对苯二酚、间苯二酚异构体、苯酚与对本醌的良好分离。方法的邻苯二酚回收率大于98％，相对偏差小于0．2％；杂质最低检测限10mg／L。This paper reports the analysis of catechol product by HPLC using a silicagel column. With hexane-isopropanol-acetic acid as mobile phase and by gradient elution method,the o-, m-, p- dihydroxybenzene isomers, phenol and p-benzoquinone can be separated fairlywell- The recovery of catechol is higher than 98%, the relative standard deviation is lessthan 0. 2%, and the detection limit of impurities is 10 mg/L.

关 键 词：苯二酚 高效液相餐谱 梯度淋洗 

分 类 号：O625.312[理学—有机化学]