43例1—7岁小儿ALL临床疗效分析  

Clinical analysis of the therapeutic effect of 43 children with ALL

作　　者：李春怀[1] 梁东[1] 王月[1] 胡晓兰[1] 王惠[1] 李潇影[1] 盖学良[1] 

机构地区：[1]吉林大学第一医院小儿血液组,130021

出　　处：《中国妇幼保健》2007年第3期414-416,共3页Maternal and Child Health Care of China

摘　　要：目的：探讨小儿急性淋巴细胞自血病（ALL）的治疗效果。方法：应用全国小儿ALL诊疗建议（第二次修订草案）治疗43例1-7岁小儿ALL。结果：43例患儿总CR率97．7％，无事故生存（EVS）率：1年为（97．67±2．30）％，2～4年为（95．29±3．25）％，5年以上为（73．53±8．47）％。结论：应用全国小儿ALL诊疗建议（第二次修订革案）治疗1～7岁小儿ALL效果比较好，毒副作用较轻，患儿能够耐受，1～7岁ALL患儿有更多的治愈机会，此方案比较适合我国国情。Objective： To explore the curative effect of children with acute lymphoblastie leukemia （ALL） . Methods： The National Children ALL Recommend of Diagnosis and Therapy was used to treat 43 children with ALL. Results： The complete remission rate reached 97. 7%, the EFS rates were respectively （97. 67±2. 30）%, （95.29±3. 25）%, （73. 53±8.47）% in 1 year, 2～4 years and 5 years. Conclusion： The effect of applying the National Children ALL Recommend is relatively good, the toxic and side effects of the treatment is relatively slight and tolerable. The results come to a conclusion that the treatment protocol is fit for Chinese children.

关 键 词：儿童 急性淋巴细胞白血病 缓解率 无事故生存率 

分 类 号：R725.5[医药卫生—儿科]