高原红细胞增多症患者血清甲状腺激素变化及其临床意义  

Alteration of Serum Thyroid Hormone Level in Patients with High Altitude Polycythemia

作　　者：李燕[1] 雷应权[2] 罗肇祥[2] 

机构地区：[1]西藏自治区第一人民医院内6科,西藏拉萨850000 [2]解放军第41医院检验科,西藏山南870000

出　　处：《临床军医杂志》2007年第1期43-44,共2页Clinical Journal of Medical Officers

摘　　要：目的探讨高原红细胞增多症(HAPC)患者血清甲状腺激素的变化及其临床意义。方法用酶联免疫法测定61例HAPC患者及33名正常对照者的血清甲状腺激素总三碘甲状腺原氨酸(T3)、总甲状腺素(T4),促甲状腺素(TSH)水平。结果高原红细胞增多症患者T3,T4水平均值均显著低于对照者(P<0.05),但TSH水平均值与对照者比较差别无显著性意义(P>0.05)。T3,T4水平变化与其病理程度有关。结论HAPC患者血清T3,T4水平明显低于正常人,测定血清甲状腺激素水平有助于判断HAPC患者病情的严重程度。Objective To investigate the alteration of serum thyroid hormone level in the patients with high altitude polycythemia （HAPC） and its clinical significance. Methods Serum thyroid hormone level was measured by enzyme-linked immunosorbent assay （ELISA） in 61 patients with HAPC, and in 30 healthy subjects as controls. Results The serum T3 and T4 levels were significantly lower in the patients of HAPC than in the controls （ P 〈 0.05 ）. There was no significant difference in serum TSH level between the HAPC patients and the heahhy controls （ P 〉 0.05 ）. Conclusion The serum thyroid hormone level is a useful indicator for the disease severity and the prognosis of HAPC patients.

关 键 词：高海拔 红细胞增多症 甲状腺激素 

分 类 号：R555.1[医药卫生—血液循环系统疾病]