新藤黄酸提取工艺的优化研究  

Optimization of Extracting Process of Neo-gambogic Acid

作　　者：刘修树[1] 周娟[1] 黄鹏[1] 马翔[1] 周晶[1] 王效山[1] 

机构地区：[1]安徽中医学院药学院,安徽合肥230038

出　　处：《安徽中医学院学报》2007年第1期54-55,共2页Journal of Anhui Traditional Chinese Medical College

摘　　要：目的:探讨回流提取新藤黄酸的最佳工艺。方法:以新藤黄酸含量为考察指标,采用正交试验法优选提取工艺。结果:溶剂的浓度对提取量有显著影响,其次的影响因素为提取时间、提取次数、溶剂的量。结论:提取新藤黄酸的最佳工艺为:12倍量的甲醇,提取3次,每次3 h。Objective： To explore the best extracting process of neo-gambogic acid. Methods ： The content of neogambogic acid was used as observation index. The extracting process was optimized by orthogonal design. Results： The solvent concentration had more influence on extraction as compared with the other three factors, and the next influencing factors were as follows： Duration of extraction, times of extraction and amount of solvent. Conclusion：The optimum process was as follows：12 times of methanol,refluxing and extracting for 3 times,3 hours each time.

关 键 词：新藤黄酸 正交设计 提取工艺 

分 类 号：TQ460.6[化学工程—制药化工]