N'-取代-4-卤代-N-甲基-4'-甲烷磺酰氨基二苯甲酮腙衍生物的合成与生物活性  

Synthesis and Biological Activity of N'-Substituted-4-halogenated-N-methyl-4'- methanesulfanilamide Benzophenonehydrazone Derivatives

作　　者：刘成荡[1] 夏旭建[2] 郁林军[2] 邢家华[2] 陈杰[2] 彭伟立[2] 

机构地区：[1]浙江工业大学农药研究所,杭州310014 [2]浙江省化工研究院,杭州310023

出　　处：《农药》2007年第2期97-99,102,共4页Agrochemicals

摘　　要：以对硝基苯甲酰氯、卤代苯、甲烷磺酰氯、水合肼等为原料合成4-卤代-N-甲基-4'-甲烷磺酰氨基二苯甲酮腙,后者与酰氯、醛和酮等反应得到21种新型N'-取代-4-卤代-N-甲基-4'-甲烷磺酰氨基二苯甲酮腙衍生物。所得化合物结构均经1H NMR和MS表征;初步生物活性测试表明这些化合物具有良好的杀虫活性。A series of N＇-substituted-4- halogine -N-methyl-4-methanesulfanilamide benzophenonehydrazone were synthesized using 4-nitrobenzoyl chloride, halogenatebenzene, methanesulfonyl chloride, hydrazine hydrate as starting materials,which was then treated with various aldehyde and ketone in basic condition to give twenty-one novel N-substituted -4-halogenated-N-methyl-4- benzophenonehydrazone derivatives.The structures of the products were characterized by ^1H NMR and MS Preliminary bioassay indicated that some compounds had some insecticidal activities.

关 键 词：对硝基苯甲酰氯 二苯甲酮腙 合成 生物活性 杀虫活性 

分 类 号：TQ450.21[化学工程—农药化工]