低分子肝素皮下注射局部压迫时间的研究  

Study on the Local Pressing Time after the Injecfion of LMWH

作　　者：杨桂燕[1] 郝凌 

机构地区：[1]黑龙江省电力医院,黑龙江哈尔滨150036 [2]密山市卫生学校,黑龙江密山158300

出　　处：《中国初级卫生保健》2007年第2期85-87,共3页Chinese Primary Health Care

摘　　要：目的探讨低分子肝素皮下注射局部压迫时间与皮下出血发生率及出血面积的关系,同时找出较为有效的压迫时间,以减少皮下出血的发生及减小出血面积。方法选择神经内科脑梗死患者使用低分子肝素皮下注射治疗者30例,将每例患者5次皮下注射分为5组,每组的压迫时间随机定为1min、2min、3min、4min、5min,10h后观察皮下出血的例次及出血面积的大小。结果低分子肝素皮下注射局部不同压迫时间与皮下出血存在统计学差异,且3min组与2min组、1min组比较具有统计学差异,P<0.05,而其他相邻组间无统计学差异;局部不同压迫时间与出血面积存在统计学差异,且面积较大(大于1cm×1cm),出血率在3min组与2min组、1min组之间有统计学差异,P<0.05,而其他相邻组间无统计学差异。结论低分子肝素皮下注射后局部压迫3min可以有效降低皮下出血率及较大面积出血率。OBJECTIVE To investigate the realtionship among the local pressing time the incidence and the size of subcutaneous hemorrhage, and find a optimum pressing time in order to reduce the incidence and the size of subcutaneous hemorrage after the injection of low molecular weight heparin （LMWH） . METHODS The 30 patients, who were undergone cerebral infarction of neurological department and received LMWH for treaty for 5 times selected. The pressing time after the injection were randomized into 1, 2, 3, 4 and 5 minutes respectively. The incidence and the size of subcutaneous hemorrhage were measured after 10 hours. RESULTS With regard to both the incidence and the size of subcutaneous hemorrhage, there was significantly difference in the five groups. Compared with the 2- minute group and 1-minute group, the incidence of subcutaneous hemorrhage and the occurrence of larger size （〉1 cm×1 cm） were significantly different in 3-miunte group, P〈0.05, while there was no difference between other adjacent groups. CONCLUSION Pressing for three minutes can effectively reduce the incidence and the size of subcutaneous hemorrhage resulted from subcutaneous injection of LMWH.

关 键 词：低分子肝毒 下注射 压迫时间 出血 

分 类 号：R973.2[医药卫生—药品]