2,3,4-三氟苯胺的合成研究  

Study on Synthesis of 2,3,4-Trifluoroaniline

作　　者：曾台彪[1] 肖友军[1] 梁飞[1] 彭艳[1] 

机构地区：[1]江西理工大学材料与化学工程学院,江西赣州341000

出　　处：《精细与专用化学品》2007年第3期18-20,共3页Fine and Specialty Chemicals

摘　　要：以2，3，4-三氟硝基苯为原料，乙醇为溶剂，在催化剂作用下经还原合成2，3，4-三氟苯胺。并对其合成工艺中的影响因素进行研究，获得最佳工艺条件为：反应温度65—70℃，氢气压力0．1-0．2MPa，m（2，3，4-三氟硝基苯）：m（自制催化剂）=70．8：1．0。在此最佳工艺条件下，得到的产品纯度为99．3％，收率达97．5％。2,3,4-Trifluoroaniline was synthesized from 2,3,4-trifluoronitrobenzene in the medium of ethanol with Raney-Ni as catalyst. The factors influencing on the synthetic process were investigated and the optimum conditions were obtained, i.e. the mass ratio of 2,3,4-trifluoronitrobenzene to self-made Raney-Ni catalyst was 70. 8： 1.0, reaction tem- perature of nitration was 65 -70℃, the pressure of hydrogen was 0. 1 ~ 0. 2 MPa. Under the optimum conditions, the final 2,3,4-trifluoroaniline product could he obtained with purity of 99. 3% , the yield was 97. 5%.

关 键 词：三氟苯胺 还原合成 最佳工艺条件 三氟硝基苯 影响因素 合成工艺 反应温度 氢气压力 

分 类 号：TQ246.31[化学工程—有机化工]