过滤型络合铜纳米高分子复合材料输精管节育器对雄犬精液的影响  

Influence of Filtering Nano-copper Complex/polymer Composites Intravas Device on the Semem of Male Dog

作　　者：黄勋彬[1] 索进平[2] 陈春友[3] 杜庆玲[1] 沈继云[1] 周洁玲[1] 

机构地区：[1]华中科技大学同济医学院计划生育研究所 [2]华中科技大学材料科学与工程学院 [3]华中科技大学同济医学院实验动物中心,武汉430030

出　　处：《生殖与避孕》2007年第1期31-33,37,共4页Reproduction and Contraception

基　　金：2004年华中科技大学医工;医理交叉科研基金;湖北省人口与计划生育委员会科研基金资助(2005-2)

摘　　要：目的：验证过滤型络合铜纳米高分子复合材料输精管节育器(IVD)对雄犬的节育作用。方法：选雄性成年Beagle犬6只,手术植入IVD,术后1个月、3个月、6个月和12个月各采集犬精液,分别检测精子密度、精子活动力和精浆α-糖苷酶,并以仅做假手术的对照组(2只)作对照。结果：手术植入IVD后,雄犬精液中精子含量显著下降,3个月后精液中没有检测到活精子。结论：植入过滤型络合铜纳米高分子复合材料IVD可显著降低雄犬精液中精子的密度和活动力,是一种值得进一步研究的非阻塞性IVD。Objective： To proof the comtra ceptive effect of the filtering nano-copper complex/polymer composites intravas device （IVD） in dogs. Methods： Eight male adult beagel dogs were collected, 6 of them were planted with IVD in their vas deferens and 2 as the control. Their semen were collected to test sperm densities, sperm activities in 1 month, 3 months, 6 months and 12 months after the operation. Results： The densities of sperms were reduced significantly after the IVD was implanted, no viable sperms were found in the 3rd month. Conclusion： The filtering nano-copper complex/polymer composites IVD can reduce the densities of dog＇s sperms significantly.

关 键 词：纳米 CA^2+ 输精管 节育器 犬 

分 类 号：R318.08[医药卫生—生物医学工程] R169.4[医药卫生—基础医学]