HA(+ZrO_2+Y_2O_3)/Ti_6Al_4V复合涂层的微结构与生物活性  

Microstructure and Bioactivity of HA(+ZrO_2+Y_2O_3)/Ti_6Al_4V Composite Coatings

作　　者：赵玉涛[1] 程晓农[1] 戴起勋[1] 林东洋 李素敏[1] 

机构地区：[1]江苏大学材料科学与工程学院,镇江212013

出　　处：《中国生物医学工程学报》2007年第1期116-120,125,共6页Chinese Journal of Biomedical Engineering

基　　金：江苏省自然科学基金资助项目(BK2003051);江苏省复合材料工程技术研究中心研发项目(BM2003014)

摘　　要：采用射频磁控溅射法成功制备了HA(+ZrO2+Y2O3)/Ti6Al4V生物复合涂层。借助于XRD、SEM、FTIR及AFM等对溅射涂层的相组成、微观形貌和界面结合进行了研究,并以模拟体液试验探讨了涂层的生物活性。实验结果表明:磁控溅射的复合涂层呈非晶态,经过退火处理,可以使其完全转化为晶态;复合涂层的微观表面凹凸不平,并呈现网状结构和较多的孔隙,其孔隙直径约为0.5μm^2μm;涂层的生长模式为层状加岛状生长;复合涂层在模拟体液中浸泡一段时间后,表面覆盖一层新生物质——含有CO32-的类骨磷灰石,其晶粒非常小,它与自然骨中无机相的结构成份相似,因此复合涂层具有良好生物相容性和生物活性。HA（＋ZrO2＋Y2O3）/Ti6Al4V composite coatings have been fabricated successfully by radio frequency magnetron sputtering technique. The surface and interface morphology, phase composition and chemical structure of these composite coatings are characterized under scanning electron microscopy （SEM）, X-ray diffraction （XRD）, and Fourier transform infrared spectroscopy （FTIR）. Experimental results show that the amorphous coating deposited by RF magnetron sputtering can be transferred perfectly into the crystalline structure and restored OH^- group by postannealing. The surface morphology of composite coatings is coarse and uneven with the well-distributed concaves. The average diameter of these concaves is in the range of 0.5μm - 2μm. These concaves will greatly increase the microsurface area of coating. Results of simulated body fluid （SBF） test indicate that a new substance on the surface of HA （ ＋ ZrO2 ＋ Y2O3 ）composite coating has been produced after the composite coating was immersed in simulated body fluid （SBF）. This substance is bone-like apatite containing CO^2-3 group characterized by FTIR. It has very small grain size and amorphous structure. Its structure and composition are similar to that of natural bone. Thus, HA（＋ZrO2＋Y2O3）/Ti6Al4V composite coatings have good biocompatibility and bioactivity.

关 键 词：HA(+ZrO2+Y2O3)复合涂层 射频磁控溅射 结合强度 生物活性 

分 类 号：TQ174[化学工程—陶瓷工业]