抗生丸对骨质增生患者血浆中神经递质和调质的影响  

Effects of Kangshengwan on Neurotransmitter and Modulator in Human Plasma of Patients with Hyperosteogeny

作　　者：雷亚锋 罗朝莉 王冬 

机构地区：[1]解放军第281医院,秦皇岛市066100

出　　处：《中国药房》2007年第6期457-458,共2页China Pharmacy

摘　　要：目的:研究抗生丸对骨质增生患者血浆中神经递质和调质的影响,探讨其对骨质增生的疗效。方法:应用放射免疫法,对治疗组150例骨质增生患者血浆中血管紧张素Ⅱ、强啡肽、P物质、6-酮-前列环素、血栓素B2的含量进行测定;并设正常组(20例)、对照组(20例)进行比较。结果:治疗组与正常组治疗前比较有显著性差异(P<0.05),治疗后比较无显著性差异(P>0.05)。治疗组治疗前、后比较有显著性差异(P<0.05);对照组治疗前、后比较无显著性差异(P>0.05)。结论:抗生丸对骨质增生患者具有一定治疗作用,对血浆中神经递质和调质具有调节作用。OBJECTIVE： To study the effects of Kangshengwan on the neurotransmitter and modulator in the human plasma of patients with hyperosteogeny, and discuss its curative efficacy in treatment of hyperosteogeny. METHODS： Radioimmunoassay was applied to identify the contents of angiotensin ANG- Ⅱ , dynorphin（DYNA）, SP.6-keto- PGFla and TXB2 in the human plasma of 150 treatment - group patients with hyperosteogeny. The normal group （20 cases） and comparator group （20 cases） were established for comparison. RESULTS： The treatment group and normal group showed significant difference before treatment （P〈0.05）, and insignificant difference after treatment（P 〉 0.05） . The treatment group showed significant difference before and after treatment （P 〈 0.05）, while the comparator group showed insignificant difference before and after treatment （P 〉 0.05） . CONCLUSION： Kangshengwan is shown to have certain therapeutic action on patients with hyperosteogeny and regulating effect on blood plasma neurotransmitter and modulator.

关 键 词：抗生丸 骨质增生 神经递质 调质 

分 类 号：R283.64[医药卫生—中药学] R681.55[医药卫生—中医学]