2002年至2006年阴沟肠杆菌耐药性监测分析  

Prevalence and Resistant Characteristics of Clinical Isolates of Enterobacter cloacae from 2002 to 2006

作　　者：李岩[1] 许淑珍[1] 苏建荣[1] 刘志远[1] 张淑兰[1] 

机构地区：[1]首都医科大学附属北京友谊医院检验中心,北京100050

出　　处：《中国实验诊断学》2007年第2期241-243,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的调查我院临床分离的阴沟肠杆菌耐药性变化特点,为临床合理使用抗菌药物提供依据。方法菌株鉴定采用Vitek-AMS鉴定,药敏试验采用纸片扩散法。结果阴沟肠杆菌对头孢菌素类、喹诺酮类等多种抗菌药物呈现耐药性增高。对头孢他啶与头孢噻肟的不敏感率为45.3%及52.9%。头孢吡肟、亚胺培南,仍然对阴沟肠杆菌保持较高活性。结论阴沟肠杆菌已呈现出多重耐药性,因此临床应有效地合理选择使用抗生素。Objective To investigate tile resistant characteristics of clinical isolates of Enterobacter cloacae. Methods Clinical isolates of Enterobacter cloacae were identified by Vitek-AMS and all drugs were tested by disk diffusion methods. Results The drug resistance of E. cloacae was increased to antibiotics, such as cephalospofins, quinolones, et al. Their non-susceptivity rates to ceftazidime and eefotaxime were 45.3% and 52.9% respectively. It was susceptible to eefepirne and imipenem. Conclusion Multidrugresistant strains of E. cloacae is remarkable. We should pay attention to change and use antibiotics reasonably in clinical chemotherapy.

关 键 词：阴沟杆菌 耐药性 抗生素 

分 类 号：R446.5[医药卫生—诊断学]