舒唐络胶囊质量标准研究  

Quality Standard for Shutangluo Capsule

作　　者：孙晶[1,2] 贾晓斌[1] 陈彦[1] 

机构地区：[1]江苏省中医药研究院,江苏省现代中药制剂工程技术研究中心,江苏南京210028 [2]广州中一药业

出　　处：《上海中医药大学学报》2007年第1期60-63,共4页Academic Journal of Shanghai University of Traditional Chinese Medicine

基　　金：江苏省科技厅社会发展项目(BS2002061)

摘　　要：目的:建立舒唐络胶囊的质量标准。方法:采用薄层色谱法对黄连、葛根、生地、卫矛进行定性鉴别;并应用高效液相色谱法对其中的盐酸小檗碱进行含量测定。结果:薄层色谱法均能对黄连、葛根、生地黄、卫矛进行专属定性分析;盐酸小檗碱在0.1092μg～0.6552μ(gr=0.9998)范围内线性关系良好,平均回收率为102.09%,RSD=1.62(%n=6)。结论:所建立的方法可准确地进行定性、定量检测,能排除其他成分干扰,重复性好,可作为舒唐络胶囊的质量控制和评价。Objective：To establish the quality standard for Shutangluo Capsule. Methods： Radix rehmanniae, radix pueradae, lignum aliformis euonymi, ddzoma coptidls in Shutangluo Capsule were identified by TLC; the content of berbefine hydrachlofide in the capsule was assayed by HPLC. Results： Radix rehmanniae, radix pueradae, lignm aliformis euonymi, ddzoma coptidis could be identified by TLC; Berberine showed a good linear relationship at the range of 0.1092 μg-0.6552 μg （r=0.9998）- the average recovery rate was 102.09% and RSD was 1.62% （n=6）. Conclusion： The method is accurate, and can be used for the quality control of Shutangluo Capsule.

关 键 词：舒唐络胶囊 TLC HPLC 盐酸小檗碱 质量标准 

分 类 号：R286[医药卫生—中药学]