马鞍山市志贺菌福氏4c生物亚型生物学特性及感染分析  

Analysis of biologic characteristic and infection of shigella flexneri 4c in Ma′anshan city

作　　者：陈道利[1] 胡万富[2] 冯玉华[1] 霍开兰[1] 詹圣伟[1] 曹多志[1] 朱明[1] 陈谨[1] 喻佰启[3] 张玲[3] 胡江[4] 甄炯[3] 邓国支 

机构地区：[1]安徽省马鞍山市疾病预防控制中心,安徽马鞍山243000 [2]安徽省疾病预防控制中心,合肥230061 [3]安徽省马鞍山市人民医院,安徽马鞍山243000 [4]安徽省马鞍山市十七冶医院,安徽马鞍山243000 [5]安徽省马鞍山市计划生育委员会,安徽马鞍山243000

出　　处：《中国卫生检验杂志》2007年第1期36-38,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:了解马鞍山市志贺菌福氏4 c生物亚型(F4 c)的流行及分布特点、生物学特性、药物敏感性等。方法:采用常规分离、全自动微生物鉴定系统生化鉴定、血清学试验、刚果红侵袭力检测及Ep i info 2000统计软件分析,掌握福氏4 c生物亚型的生物学基本特性及人类感染统计学数据。结果:从428份标本分离的67株志贺菌中检出福氏4 c生物亚型37株,从45株赠送菌株中鉴定22株福氏4 c生物亚型,分别占检出菌株数的55.2%和48.9%;59株福氏4 c生物亚型的生物学特性与福氏其它血清型别的基本一致,完全符合志贺菌生化定义;侵袭力试验结果显示只有1株福氏4 c生物亚型为阴性,其余均为阳性;福氏4 c生物亚型耐药模式与其它志贺菌血清型存在一定差异;软件统计结果说明福氏4 c生物亚型感染人类具有普遍性,与年龄、性别无差异。结论:志贺菌福氏4 c生物亚型业已成为马鞍山地区志贺菌感染的主要流行株,为进一步掌握F4 c的流行动态,探讨其分子水平的流行状况,将通过分子流行病学方法追溯传染源,以达到将其消灭在初始阶段的目的。Objective：To realize characteristic prevalence distributing, biologic characteristic, bacteriophage sensitive test of shigalla flexneri 4c subtype（ F4c ） in Ma＇anshan city. Methods：Routine isolation, identifier in AMS, serology test, Congo red invadability examination and analysis in statistic software Epi info 2000 were used for basic characteristic and data on h,man infection of F4c. Results：F4c were been detected 37 strains of 67strains from 428 samples, to donate towards 45 strains identified 22 strains. Parting was 55. 2% and 48. 9% of account. Fifty - nine strains of F4c have been had biologic characteristic with other serology type. It accorded completely define of shigella, only one strain was negative for invadability examination and others were positive. F4c was different in antibiotic resistanc from others. F4c was elucidated to have universal infection in human by Epi info 2000. It was not associated with sex and ages. Conclusion： F4c is the major strain which infecting shigella in Ma＇anshan area. It is going to search fountainhead infectant,for predominating dynamic F4e.

关 键 词：福氏4c生物亚型 生物学特性 药物敏感性 

分 类 号：R378.25[医药卫生—病原生物学]