男性精液质量与宫腔内人工受精妊娠率的关系  

The relationship of sperm parameters with pregnancy outcome after intrauterine insemination

作　　者：卢少明[1] 陈子江[1] 赵力新[1] 胡京美[1] 李晓[1] 张浩波[1] 

机构地区：[1]山东省立医院生殖中心,济南250021

出　　处：《临床泌尿外科杂志》2007年第2期87-89,共3页Journal of Clinical Urology

摘　　要：目的：探讨处理前后的精液特征与宫腔内人工受精（IUI）妊娠率的影响。方法：收集分析819例不育不孕患者共1060个IUI治疗周期，检测记录每个周期精液处理前后的各精液参数。根据妊娠结果分成妊娠组与非妊娠组；根据处理后精子活动总数（PTMS）分成PTMS〈5×10^6，5×10^6～〈10×10^6，10×10^6～〈20×10^6，20×10^6～〈30×10^6，≥30×10^6五组；根据处理前精子密度分为3组：少精子症、弱精子症、正常精子组。分别比较各组间的各精液参数及妊娠率。结果：1060个IUI周期共获得156例妊娠，总周期妊娠率是14．7％，总病例妊娠率是19．0％。妊娠组与非妊娠组相比，各精液参数无明显差别；上述PTMS各组妊娠率依次为2．4％、9．2％、16．4％、16．7％和18．9％，各组间差异有统计学意义（P〈0．05）。少精子症、弱精子症、正常精子组妊娠率分别是7．0％、14．3％和18.1％，后两组明显高于第1组（P〈0．05）。结论：当PTMS≥10×10^6以上时，IUI治疗才有可能获得较为理想的妊娠率；少精子症患者IUI妊娠率明显低于弱精子症、正常精子组的患者。Objective： To explore the relationship of sperm parameters with pregnancy outcome after intrauterine insemination. Methods： 819 infertile couples underwent 1060 cycles of husband IUI. The semen parameters were recorded for each insemination. The patients were divided into 2 groups according to pregnancy, into 5 groups according to PTMS： PTMS〈5×10^6,5×10^6～〈10×10^6,10×10^6～〈20×10^6,20×10^6～〈30×10^6,≥30×10^6 , and into 3 groups： oligo-sperm, asthenosperm and normal sperm. Results： Pregnancy occurred in 156 cycles, results in an overall pregnancy rate per cycle of 14.7%, and a couple pregnancy rate of 19.0%. No significant difference was found between pregnancy and nonpregnancy cycles, the pregnancy rate of every PTMS group was 2. 4%.9.2% ,16.4%.16.7% and 18.9% respectively, and the difference among them was significant, the pregnancy rate of oligosperm, asthenosperm and normal sperm groups was 7.0% ,14.3% and 18.1% respectively, the first one was significantly lower than the other two groups. Conclusions： 1. Semen parameters with greater than 10 106 PTMS are significantly more likely to result in a pregnancy. 2. the pregnancy rate of oligosperm was significantly lower than the other asthenosperm and normal sperm groups.

关 键 词：精液参数 宫腔内人工受精 少精症 弱精症 妊娠率 

分 类 号：R698.2[医药卫生—泌尿科学]