血栓素A_2合成抑制剂——川芎嗪改善大鼠胰腺保存效果的实验研究  

Experimental research on the effect of thromboxane synthase inhibitor ligustrazine on rat pancreas preservation

作　　者：陈刚[1] 张肖红[1] 陈实[1] 

机构地区：[1]同济医科大学附属同济医院器官移植研究所,武汉430030

出　　处：《中华器官移植杂志》1996年第4期172-173,共2页Chinese Journal of Organ Transplantation

摘　　要：本实验研究了川芎嗪加入本所自制的 WMO-1号器官保存液对大鼠胰腺保存效果的影响。结果表明,WMO-1号保存液对大鼠胰腺的确切保存时限为12小时,18小时保存存活率仅为1/3,加入川芎嗪可使保存时限延长至18小时,24小时保存存活率为1/3。证明川芎嗪确能改善胰腺保存。In this study the rat pancreas transplant model was used to determine the effect of ligustrazine in WMO-1 solution on pancreas preservation.The result showed that the exact preservation time of WMO-1 solution for pancreas was 12h,and when pancreas was preserved for 18h,the survival rate was 1/3.Addition of ligustrazine to WMO-1 solution could prolong the preservation time to 18h,and when pancreas was preserved for 24h,the survival rate is 1/3. These findings proved that ligustrazine can improve pancreas preservation.

关 键 词：川芎嗪 胰腺保存 保存效果 

分 类 号：R657.5[医药卫生—外科学]