胚胎中脑黑质脑内移植治疗帕金森病长期随访观察  

Following-up study of transplantation of fetal substantia nigra for Parkinson's disease

作　　者：吴承远[1] 张庆林[1] 孙敬熙[2] 王树新[3] 徐淑军[1] 周茂德[1] 鲍秀峰[1] 黄崇熙[2] 赵经郊[1] 

机构地区：[1]山东医科大学附属医院,济南250012 [2]青岛市立医院 [3]解放军第88医院

出　　处：《中华器官移植杂志》1996年第4期174-176,共3页Chinese Journal of Organ Transplantation

摘　　要：本文报告采用胚胎中脑黑质细胞脑内移植治疗6例晚期帕金森病,包括1例脑立体定向丘脑毁损后震颤复发者,经移植治疗后获得良好放果。本组病例书氏计分平均从21分降至11分。其中2例经术后3、9、14个月 CT、MRI 随访,脑内移植物体积增大,症状和体征明显改善。Presented in this paper is treatment of 6 cases of late-stage Parkinson's disease treated by transplantation of fetal substantial nigra.Our series included 1 patient with stereota thelamectomy.Satisfactory results were achieved in all patients.The Wehster's scores were re- duced form 21 points to 11 points.The follow-up study 3,9,14 months after transplantation showed growth of intracranial grafts as confirmed by CT and MRI and improvement of symptoms and signs.

关 键 词：帕金森病 黑质移植 胎脑移植 

分 类 号：R651.11[医药卫生—外科学] R742.5[医药卫生—临床医学]