超声造影连续灌注曲线数学模型适用性初步研究  

Pilot study of mathmatic model for flash-replenishment

作　　者：周翔[1] 张艳容[1] 项飞翔[1] 林铤[1] 严天蔚[1] 谢明星[1] 王新房[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院超声影像科,武汉430022

出　　处：《中华超声影像学杂志》2007年第1期72-75,共4页Chinese Journal of Ultrasonography

摘　　要：目的研究Flash-replenishment技术在不同流速下的数学模型拟合的可行性。方法建立微循环体外模型，通过蠕动泵一透析纤维系统模拟微循环血流。分别测定流速1～30mm／s的灌注曲线形态，并进行数学拟合。结果低流速（〈10mm／s）时灌注曲线呈伽马“s”型曲线形态，高流速（〉10mm／s）时呈典型单指数函数曲线形态。结论对于微循环血流，流速大于10mm／s适用于单指数函数进行拟合。当流速小于10mm／s时需进一步深入研究其他可行性模型。Objective To investigate the feasibility of mono-exponential function for flashreplenishment perfusion technique. Methods A in-vitro model for microcirculation was build up. The flow velocity was analyzed from 1 mm/s to 30 mm/s by pump-dialysis fiber system. The time-intensity curve was studied for every flow rate. Results The shape of time-intensity for low flow rate（〈1 0mm/s） was Sigma shape, mono-exponential shape for high flow rate （〉 10 ram/s）. Conclusions The mono-exponential function is not good function for fit of low flow rate time-intensity curve.

关 键 词：超声检查 造影剂 微循环 模型 心血管 

分 类 号：R686[医药卫生—骨科学]