自制环糊精衍生物毛细管柱对甲酚二甲酚位置异构体的分离研究  

Separation of Cresol and Xylenol Homologue Isomers by Capillary Gas Chromatography with β-Cyclodextrin Derivatives as Stationary Phase

作　　者：秦金平[1] 马珂[1] 喻红梅[2] 陈长林[1] 

机构地区：[1]南京工业大学化学化工学院,江苏南京210009 [2]南通大学化学化工学院,江苏南通226007

出　　处：《化学世界》2006年第9期530-532,523,共4页Chemical World

基　　金：国家自然科学基金资助项目(20476047)

摘　　要：采用两种环糊精衍生物(全甲基-β-环糊精;2,3-二-O-苄基-6-O-叔丁基二甲基-β-环糊精)作固定相,研制了4根毛细管色谱柱。并考察了稀释剂比例以及柱温对酚系物异构体分离性能的影响。结果表明全甲基环糊精类毛细管柱对甲酚二甲酚位置异构体能完全分离,苄基类环糊精色谱柱对酚系物有一定的分离能力,但间甲酚与对甲酚不能基线分离。Four capillary gas chromatographic columns were prepared using two β-cyclodextrin derivatives（permethylated β-cyelodextrin, 2, 3-di- O-benzyl-6- O-tert-butydimethysilyl-β-eyelodextrin ） as the stationary phase. The effects of proportion of diluents and column temperature on separation properties were studied. The results show that permethylated- β-cyelodextfin columns have high selectivity for the phenols homologue isomers, whereas 2,3-di-O-benzyl-6-O-tert- butydimethysilyl-fl-eyelodextrin columns can also separate them, but they can not offer a baseline resolution of m-cresol and p-cresol. 　

关 键 词：环糊精 毛细管色谱 甲酚 二甲酚 位置异构体 

分 类 号：O658[理学—分析化学]