用水迷宫建立大鼠空间辨别性学习记忆模型  

Establishing the Spatial Learning and Memory of Rats with Water Maze

作　　者：冯力民[1] 吴真[1] 佟也芒[2] 

机构地区：[1]北华大学医学院,吉林吉林132013 [2]吉林市中心医院,吉林吉林132011

出　　处：《北华大学学报（自然科学版）》2007年第1期46-49,共4页Journal of Beihua University（Natural Science）

基　　金：吉林省科技厅基金项目资助(2004031-09):

摘　　要：目的探索脑形态与脑功能结合的动物模型建立方法．方法用水迷宫训练大鼠建立空间辨别性学习记忆模型．结果用水迷宫每天训练10次，连续7d即可这到预定的模型标准；在建立模型的过程中发现在训练的第5天有学习的平台期出现．结论水迷宫训练实验能有效的使大鼠建立空间辨别性学习记忆能力．Objective Seeking behavioral experiment method which could appreciate both memory and morphology change of rats. Methods The experiment was performed spatial learning and memory animal model with water maze. Results The rats were trained for ten times every day with water maze, the desired model level could be established for continuous seven days; and plateau period of learning and memory appeared at the fifth day during the process of establishing model. Conclusion It is effective in using the water maze to appreciate the motional learning and memory of rats.

关 键 词：水迷宫 学习记忆 动物模型 

分 类 号：R332[医药卫生—人体生理学]