浸出性蛋白质量与尿结石类型关系的实验探讨  

Experimental Study About the Relation Between Content of Soaked-out-protein and Typess of Urinary Calculus

作　　者：许文荣 顾可梁 周建忠 

出　　处：《镇江医学院学报》1996年第4期307-308,共2页Journal of Zhenjiang Medical College

基　　金：江苏省卫生厅自然科学基金

摘　　要：采用ＣＢＢ－Ｇ２５０法对１９６份尿结石标本进行浸出性蛋白质定量分析，尿结石中浸出性蛋白质含量存在较大差别，其中未测出蛋白质量有６份（占３．１０％），浸出性蛋白质量在１ｍｇ－１０ｍｇ／ｇ结石粉有１６８份（占８５．７％），１０ｍｇ／ｇ～２０ｍｇ／ｇ结石粉有１６份（占８．１０％），浸出性蛋白质量大于２０ｍｇ／ｇ结石粉有６份（占３．１０％）。本文还对尿结石浸出性蛋白质定量与定性配合研究，８８份尿结石分为五组，实验发现：草酸钙、磷、镁、氨类结石（尿酸阴性、碳酸阴性）和氨基酸、蛋白质类结石（草酸、尿酸、碳酸、磷、氨均为阴性）两组浸出性蛋白质量分别为８．４０±１０．２０，７．７９±４．９９．明显高于其它几组（Ｐ＜０．０５）。证明：感染性尿结石蛋白质量有明显差别，说明蛋白质在这两类尿结石形成中具有更重要的意义。Quantitative analysis of content of soaked-out-protein from 196 urinary calculus samples was carried out with CBB-G250 method.The content was different in the samples: Negative in 6 samples(3.10%);In a range of 1mg/g～10mg/g calculus powder in 168 samples(85.70%);In a range of 10mg/g～20mg/g calculus powder in 16 samples(8.10%); Higher than 20mg/g calculus powder(3.10%) in 6 samples. The match test of quantity and quality of the soaked-out-protein from the urinary calculi was also performed.Eighty eitht samples were divided into five groups.It was found that the content of soaked-out-protein of calculi containing calcium oxalate,magnesium, phosphate and ammonia(Uric acid and carbonic acid negative) and that of calculi containing amino acid and proten(oxalic acid, uric acid carbonic acid, phosphate,ammoniomagnesium negative) were 8.40±10.20 and 7.79±4. 99 respectively, significantly higher than those of other groups(P<0.05). The results confirmed that content of the protein soaked out from infectious calculi was markedly different.It suggested that protein plays an important role in forming the two types of urinary calculi.

关 键 词：尿结石 蛋白质 病毒 

分 类 号：R691.402[医药卫生—泌尿科学]