慢性重型肝炎营血证的鲜生地汁治疗  

Chronic fulminate hepatitis patients treated by fresh Rehmannia juice

作　　者：贾建伟[1] 赵洁[1] 李谦[1] 马莹[1] 宋伟[1] 高丽英[1] 袁桂玉 

机构地区：[1]天津市传染病医院,天津300192

出　　处：《中西医结合肝病杂志》2007年第1期7-9,共3页Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases

基　　金：天津市卫生局中医;中西医结合科研专项基金(No.022-03012)

摘　　要：目的:观察口服鲜生地汁对慢性重型肝炎(重肝)早/中期(中医营血证)患者的疗效。方法:患者分为两组,在给予重肝综合治疗的同时,治疗组患者口服鲜生地汁,100m l/d(分服);对照组患者口服乳果糖10ml/次,3次/d,分别于治疗前及第2周末记录患者症状,检测肝功能、凝血酶原活动度及血浆内毒素、细胞因子。结果:两组患者腹胀及大便干结症状、肝功能均好转;血浆内毒素下降;肿瘤坏死因子-α降低;凝血酶原活动度增加;治疗组效果优于对照组。治疗组患者口干、烦热症状亦有明显改善。结论:口服鲜生地汁可有效减轻重肝患者内毒素血症、降低细胞因子水平,并在改善口干、烦热等营血证表现及凝血机制方面与乳果糖比较具有明显优势。Objective ： To observe the efficacy of fresh Rehmannia juice therapy for chronic fulminate hepatitis patients with curative effect. Methods： Sixty- two chronic fulminate hepatitis patients received either fresh Rehmannia juice lOOml （trail group, n =31 ） or lactulose 30ml （control group, n = 31 ） every day. Registered symptom and mensurated the changes of liver function, PTA, serum endotoxin, TNF-α and IL-1 at the initial stage and the end of 2nd week in trail group and contrl group, Results： At the end of treatment, abdominal flatulence, intestinal stasis, liver function, PTA, serum endotoxin, TNF-α of either trail group or control group had visible improvement. The change in trail group was evidenter than in control group. Dry mouth and dysphoria with smothery sensation in trail group had also visible improvement, Conclusion： Fresh Rehmannia Juice therapy for chronic fulminate hepatitis patients can reduce serum endotoxin and TNF-α. It has advantage in improvement in Yingxue syndrome and cruor.

关 键 词：慢性重型肝炎 鲜生地汁/治疗应用 乳果糖/治疗应用 病例对照研究 

分 类 号：R259[医药卫生—中西医结合]