急性心肌梗死患者炎性因子表达与室性心律失常的关系  

Relation between inflammatory factor level of AMI and ventricular arrhythmias

作　　者：肖华[1] 陈志坚[1] 廖玉华[1] 黄恺[1] 郭和平[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院,湖北武汉430022

出　　处：《山东医药》2007年第4期19-20,共2页Shandong Medical Journal

基　　金：国家自然科学基金资助项目(30400175)

摘　　要：目的研究急性心肌梗死(AMI)患者的炎性因子水平与心梗后室性心律失常的关系。方法不同时间点检测65例AMI患者的心肌酶谱及血浆炎性因子表达水平,并监测其心律失常情况,进行相关性分析。结果血浆炎性因子水平与心肌酶谱呈正相关(P<0.05),炎性因子表达与心梗后室性早搏Lown分级呈正相关(P<0.05),前壁AMI患者炎性因子水平较其他部位高(P<0.05)。结论AMI后炎性因子表达水平与室性心律失常存在一定关系,AMI后室性心律失常发生多的患者炎性因子表达水平高。[Objective] To investigate the relationship between inflammatory factor levels after acute myocardial infarction（AMI） and ventricular arrhythmias. [Methods]The plasma levels of myocardial enzyme and inflammatory factor in 65 AMI patients were detected at different time. Arrhythmias were monitored and correlation analysis was carried out. [Results]The plasma levels of cytokines were positively associated with myocardial enzyme and the lown class of premature ventricular contraction （PVC） （P〈0. 05）. The plasma levels in anterior AMI were higher than those of other position （P〈0.05）. [Conclusion] There was positive relationship between inflammatory factor level after AMI and ventricular arrhythmias. The plasma levels of cytokines increased with the high rate of ventricular arrhythmias.

关 键 词：心肌梗死 急性 心律失常 肿瘤坏死因子 白细胞介素6 心肌酶 

分 类 号：R541.4[医药卫生—心血管疾病]